Pharmacology in Assisted Reproductive Nursing

A highly qualified Postgraduate Certificate that prepares the nursing professional to act with safety and solvency in the Study of Male Infertility"

The main objective of this Postgraduate Certificate is to prepare nurses in the field of male infertility. This specialization is extremely necessary, since the nursing staff is involved in many of the processes carried out in the Assisted Reproduction Units, such as the performance of seminograms, the analysis and processing of samples, seminal freezing, seminal lavage or even managing the male donor bank. 

In order to prepare our students in the most complete way possible, we begin by explaining how the initial study of the patient is performed in consultation, also covering the complementary explorations that may arise, depending on the patient, as well as the genetic studies that can be performed. 

Other approaches that will be developed in the Postgraduate Certificate are the basic aspects of the seminogram, an essential technique in seminal diagnosis. Once this technique is clear, the analysis and processing of samples for the different assisted reproduction techniques will be explained in detail, to continue with other widely used techniques, semen freezing and semen washing for HIV, Hepatitis B and Hepatitis C seropositive males. 

We will explain in detail what semen donation is and how it works, three of the most widely used complementary sperm selection techniques, MACS, IMSI and hyaluronic acid based selection. 
Finally, the nursing staff will be educated in the use of antioxidants, a topic that is currently on the rise and which will be very necessary in practice. 

With this Postgraduate Certificate you will be able to combine a high intensity specialization with your professional and personal life, achieving your goals in a simple and real way"

This Postgraduate Certificate in Pharmacology in Assisted Reproductive Nursing contains the most complete and up-to-date scientific program on the market. The most important features include: 

• The latest technology in online teaching software
• A highly visual teaching system, supported by graphic and schematic contents that are easy to assimilate and understand
• Practical cases presented by practising experts
• State-of-the-art interactive video systems
• Teaching supported by telepractice
• Continuous updating and recycling systems
• Autonomous learning: full compatibility with other occupations
• Practical exercises for self-evaluation and learning verification
• Support groups and educational synergies: questions to the expert, debate and knowledge forums
• Communication with the teacher and individual reflection work
• Content that is accessible from any fixed or portable device with an Internet connection
• Complementary documentation banks permanently available, even after the Postgraduate Certificate

Acquire the necessary skills to work in the Study of Male Infertility in Assisted Reproduction, with the solvency of a high-level professional"

Our teaching staff is made up of professionals from different fields related to this specialty. In this way we ensure that we deliver the educational update we are aiming for. A multidisciplinary team of professionals prepared and experienced in different environments, who will develop the theoretical knowledge in an efficient way, but, above all, will put at the service of the Postgraduate Certificate the practical knowledge derived from their own experience: one of the differential qualities of this specialization.

This mastery of the subject matter is complemented by the effectiveness of the methodological design of this Postgraduate Certificate in Pharmacology in Assisted Reproduction for Nursing. Developed by a multidisciplinary team of Postgraduate Diplomas, it integrates the latest advances in educational technology. This way, you will be able to study with a range of comfortable and versatile multimedia tools that will give you the operability you need in your education.

The design of this program is based on Problem-Based Learning: an approach that conceives learning as a highly practical process. To achieve this remotely, we will use telepractice learning: with the help of an innovative interactive video system, and learning from an expert, you will be able to acquire the knowledge as if you were actually dealing with the scenario you are learning about. A concept that will allow you to integrate and fix learning in a more realistic and permanent way.

The learning of this Postgraduate Certificate is developed through the most advanced teaching methods in online teaching to guarantee that your effort will have the best possible results"

Our innovative telepractice concept will give you the opportunity to learn through an immersive experience, which will provide you with a faster integration and a much more realistic view of the contents: “Learning from an expert”"

The contents of taught have been developed by the different experts on this course, with a clear purpose: to ensure that our students acquire each and every one of the necessary skills to become true experts in this field. 

A complete and well-structured program that will take you to the highest standards of quality and success.  

A specialization created and directed by professional experts in Assisted Reproduction that make this Postgraduate Certificate a unique opportunity for professional growth"

Module 1. Pharmacology in Assisted Reproduction

1.1. Initial Study

1.1.1. Objectives
1.1.2. When Should It Be Done?
1.1.3. Minimum Evaluation
1.1.4. Optimal Evaluation
1.1.5. Medical History
1.1.6. Physical Exploration

1.2. Complementary Evaluations

1.2.1. Sperm Function Tests
1.2.2. Hormonal Determinations
1.2.3. Ultrasonography and Scrotal Doppler Ultrasonography
1.2.4. Transrectal Ultrasound
1.2.5. Bacteriological Study of Semen
1.2.6. Post-Orgasm Urinalysis

1.3. Genetic Studies

1.3.1. Karyotype
1.3.2. Yq Microdeletions
1.3.3. CFTR Mutations
1.3.4. Meiotic Chromosome Studies
1.3.5. FISH of Spermatozoa

1.4. Seminogram

1.4.1. Basic Considerations
1.4.2. Proper Sample Handling
1.4.3. Sample Collection

1.4.3.1. Preparation
1.4.3.2. Collection for Diagnosis
1.4.3.3. Collection for Use in Assisted Reproduction
1.4.3.4. Collection for Microbiological Analysis
1.4.3.5. Home Collection
1.4.3.6. Collection with Preservative

1.4.4. Initial Macroscopic Examination

1.4.4.1. Liquefaction
1.4.4.2. Viscosity
1.4.4.3. Appearance 
1.4.4.4. Volume
1.4.4.5. PH

1.4.5. Initial Microscopic Examination

1.4.5.1. How to Get a Representative Sample
1.4.5.2. Sample Quantity
1.4.5.3. Aggregation
1.4.5.4. Agglutination
1.4.5.5. Presence of Cellular Elements Other than Spermatozoa

1.4.6. Motility
1.4.7. Vitality
1.4.8. Concentration
1.4.9. Counting of Cells Other than Sperm Cells
1.4.10. Sperm Morphology
1.4.11. Presence of Leukocytes in Semen
1.4.12. Antispermatozoa Antibodies Test
1.4.13. Automated Analysis

1.5. Analysis and Processing of Samples for Assisted Reproduction Techniques (ART)

1.5.1. Washing
1.5.2. Swim-up
1.5.3. Density Gradients

1.6. Sperm Freezing

1.6.1. Indications
1.6.2. Cryoprotectors
1.6.3. Semen Freezing Techniques
1.6.4. Storage Containers 

1.7. Semen Washing for HIV, Hepatitis B and Hepatitis C Seropositive Males

1.7.1. Hepatitis B
1.7.2. HIV
1.7.3. Hepatitis C
1.7.4. General Considerations

1.8. Sperm Donation

1.8.1. General Aspects
1.8.2. Indications
1.8.3. Sperm Donor Considerations
1.8.4. Recommended Tests
1.8.5. Anonymity
1.8.6. Choosing the Right Donor
1.8.7. Risk
1.8.8. Cessation of Donation

1.9. Complementary Sperm Selection Techniques

1.9.1. MACS (Magnetically Marked Cell Sorting)

1.9.1.1. Biological Basis of the Technique
1.9.1.2. Indications
1.9.1.3. Advantages and Disadvantages

1.9.2. IMSI (Intracytoplasmic Injection of Morphologically Selected Spermatozoa)

1.9.2.1. Procedure
1.9.2.2. Indications
1.9.2.3. Advantages and Disadvantages

1.9.3. Selection Based on Binding to Hyaluronic Acid

1.9.3.1. Procedure
1.9.3.2. Indications
1.9.3.3. Advantages and Disadvantages

1.10. Oral Therapy Use of Antioxidants

1.10.1. Antioxidant Concept
1.10.2. Reactive Oxygen Species (ROS)
1.10.3. Factors Leading to Increased ROS in Semen
1.10.4. Damage Caused by Increased ROS in Spermatozoa
1.10.5. Antioxidant System in Semen

1.10.5.1. Enzymatic Antioxidants
1.10.5.2. Superoxide Dismutase
1.10.5.3. Catalase
1.10.5.4. Nitric Oxide Synthase
1.10.5.5. Glutathione S-Transferase
1.10.5.6. Peroxiredoxin
1.10.5.7. Thioredoxins
1.10.5.8. Glutathione Peroxidase

1.10.6. Exogenous Supplementation

1.10.6.1. Omega 3 Fatty Acids
1.10.6.2. Vitamin C
1.10.6.3. Coenzyme Q10
1.10.6.4. L-Carnitine
1.10.6.5. Vitamin E
1.10.6.6. Selenium
1.10.6.7. Zinc
1.10.6.8. Folic Acid
1.10.6.9. L-Arginine

1.10.7. Conclusions

A comprehensive teaching program, structured in well-developed teaching units, oriented towards learning that is compatible with your personal and professional life”