Elaboration and Development of Individualized Medicines

Improve your knowledge in the Elaboration and Development of Individualized Medicines through this program, where you will find the best teaching material with real clinical cases. Find out about the latest advances in the speciality here, in order to be able to carry out quality clinical practice"

The Master Formulation or, nowadays, "individualized medicine" is the essence of the pharmaceutical profession. It has been the starting point of human medicine therapeutics, when patient care was itemized.

The magistral formula understood as the medicine intended for an individualized patient, prepared by a pharmacist or under his direction, to expressly fulfill a detailed medical prescription of the medicinal substances that includes, requires that the professional activity conform to strict and faithfully reproducible procedural guidelines. In this sense, pharmacists need to be up to date and promote continuous training in the knowledge and compliance with the standards for the correct preparation and quality control of master formulas in order to achieve the required level of quality.

The main objective of the Professional Master’s Degree in Elaboration and Development of Individualized Medicines is to train pharmacists in a unique and exclusive discipline of their profession, specializing professionals who can respond to therapeutic gaps with the formulation of an individualized medicine with the quality and efficacy of an industrialized medicine.

In this sense, the Professional Master’s Degree is structured in four specific blocks, focused on the Elaboration and Development of Individualized Medicines, as well as the current legislation and the rules for the correct elaboration of master formulas and officinal preparations.

These theoretical modules will be accompanied by videos of the elaboration of different master formulas prepared by professionals, where the student will be able to visualize the modus operandi of each one of them.

Update your knowledge through the Professional Master’s Degree in Professional Master’s Degree"

This Professional Master’s Degree in Elaboration and Development of Individualized Medicines contains the most complete and up-to-date scientific program on the market. The most important features of the program include:

• Development of more than 50 clinical cases presented by experts in Master Formula
• The graphic, schematic, and practical contents with which they are created provide scientific and practical information on the disciplines that are essential for professional
• Contains practical exercises where the self-evaluation process can be carried out to improve learning
• An algorithm-based interactive learning system for decision-making in the clinical situations presented throughout the course
• Special emphasis on evidence-based medicine and research methodologies in the Elaboration and Development of Individualized Medicines
• All of this will be complemented by theoretical lessons, questions to the expert, debate forums on controversial topics, and individual reflection assignments
• Availability of content from any fixed or portable device with internet connection

This Professional Master’s Degree is the best investment you can make in the selection of a refresher program for two reasons: in addition to updating your knowledge in Elaboration and Development of Individualized Medicines, you will obtain a certificate issued by TECH Technological University”

The teaching staff includes professionals from the field of master formulation, who bring their experience to this training program, as well as renowned specialists from leading scientific societies.

Thanks to its multimedia content developed with the latest educational technology, it will allow the professional a situated and contextual learning, that is to say, a simulated environment that will provide an immersive learning programmed to train in real situations.

The design of this program focuses on Problem-Based Learning, through which the pharmaceutical professional should try to solve the different situations of professional practice that arise during the course. For this purpose, it will be assisted by an innovative interactive video system created by renowned experts in the field of the Elaboration and Development of Individualized Medicines with extensive teaching experience.

Increase your decision-making confidence by updating your knowledge through this Professional Master’s Degree"

This Professional Master’s Degree will generate a sense of confidence when performing clinical practice, which will help you to grow personally and professionally"

The structure of the contents has been designed by a team of professionals from the best research centers and universities, aware of the current relevance of training to use drugs safely and with a solid scientific basis based on evidence, and committed to quality teaching through new educational technologies.

This Professional Master’s Degree in Elaboration and Development of Individualized Medicines contains the most complete and up-to-date scientific program on the market”

Module 1. Biopharmaceutics and Pharmacokinetics

1.1. New Aspects of Galenic Pharmacy

1.1.1. Introduction
1.1.2. Chemical, Therapeutic and Biological Equivalence of Medicines
1.1.3. Biopharmaceutics and Basic Pharmacokinetics
1.1.4. Pharmaceutic Technology
1.1.5. Clinical Pharmacokinetics

1.2. Evolution of Medicines in the Body

1.2.1. LADME
1.2.2. Kinetics of LADME Processes
1.2.3. Release as a Limiting Factor of Absorption

1.3. Absorption Mechanisms

1.3.1. Passive Diffusion
1.3.2. Convective Diffusion
1.3.3. Active Transport
1.3.4. Facilitated Transport
1.3.5. Ion Pairs
1.3.6. Pinocytosis

1.4. Routes of Administration

1.4.1. Oral Route

1.4.1.1. Physiological Factors Affecting Gastrointestinal Absorption
1.4.1.2. Physicochemical Factors Limiting Absorption

1.4.2. Topical Route

1.4.2.1. Skin Structure
1.4.2.2. Factors Influencing the Absorption of Substances Through the Skin

1.4.3. Parenteral Route

1.4.3.1. Parenteral Aqueous Solutions
1.4.3.2. Delayed Parenteral Solutions

Module 2. Basic Operations in the Production of Individualized Formulas

2.1. Weighing

2.1.1. Objective
2.1.2. Scales

2.1.2.1. Calibration

2.2. Spraying

2.2.1. Importance in the Formulation and Objectives
2.2.2. Spraying Equipment

2.2.1.1. Manual
2.2.1.2. Industrial

2.2.3. Factors that Affect Spraying

4.2.3.1. Size
4.2.3.2. Texture

2.2.4. Rheological Properties

2.2.4.1. Plastic fluids
2.2.4.2. Exfoliables
2.2.4.3. Elastic

2.3. Screening

2.3.1. Description
2.3.2. Sieves
2.3.3. Sieving Procedures

2.4. Mixing and Homogenization

2.4.1. Objectives
2.4.2. Types of Mixtures
2.4.3. Homogenization Process
2.4.4. Mixing Equipment

2.5. Filtration

2.5.1. Concept
2.5.2. Filtration Systems
2.5.3. Modes of Filtration

2.5.3.1. Conventional Filtration
2.5.3.2. Microfiltration
2.5.3.3. Ultrafiltration
2.5.3.4. Reverse Osmosis
2.5.3.5. Sterilizing Filtration
2.5.3.6. Tangential Filtration

2.6. Drying

2.6.1. Types of Sounds According to their Humidity
2.6.2. Midwives in Drying
2.6.3. The Drying Process
2.6.4. Devices for Drying
2.6.5. Freeze-Drying

2.6.5.1. Stages of the Freeze-Drying Process
2.6.5.2. Applications

2.7. Sterilization

2.7.1. Heat Sterilization

2.7.1.1. Humid Heat
2.7.1.2. Dry Heat

2.7.2. Sterilization by Filtration
2.7.3. Other Types of Sterilization

Module 3. Topical Pharmaceutical Dosage Forms

3.1. Solutions

3.1.1. Aqueous Solutions
3.1.2. Alcoholic Solutions
3.1.3. Hydroalcoholic Solutions
3.1.4. Liposome Solutions or Liposomes

3.1.4.1. Liposomes and Types
3.1.4.2. Composition of Liposomes
3.1.4.3. Functions of Liposomes
3.1.4.4. Production of Liposomes Pharmacy and Industry
3.1.4.5. Quality Control

3.1.5. Foams
3.1.6. Problems in the Production of Solutions

3.2. Emulsions

3.2.1. Definition
3.2.2. Emulsion Components
3.2.3. Types of Emulsifiers
3.2.4. Production
3.2.5. HLB Balance
3.2.6. Quality Control
3.2.7. Problems and Solutions in the Production Process

3.3. Gels

3.3.1. Mechanisms for Elaborating a Gel
3.3.2. Classification of Gelling Substances
3.3.3. Quality Control
3.3.4. Problems and Solutions in the Production Process

3.4. Ointments and Pastes

3.4.1. Definition
3.4.2. Types
3.4.3. Quality Control
3.4.4. Problems and Solutions in Paste Processing

3.5. Transdermal Creams

3.5.1. Definition
3.5.2. Mechanism of Action
3.5.3. Most Common Active Ingredients in Transdermals
3.5.4. Production

3.5.4.1. PLO Gel
3.5.4.2. PEN Type TD Creams

3.5.5. Uses

3.5.5.1. Palliative Pain Therapy
3.5.5.2. HRT Therapy

3.5.6. Quality Control

3.6. Application in Dermatology of Pharmaceutical Forms for Topical Administration

3.6.1. Skin Structure and Functions

3.6.1.1. Epidermis
3.6.1.2. Dermis
3.6.1.3. Hypodermis

3.6.2. Common Pathologies
3.6.3. Master Formulas Frequently Used in Dermatology

3.7. Application in Podiatry of Pharmaceutical Forms for Topical Administration

3.7.1. The Foot
3.7.2. Common Pathologies
3.7.3. Master Formulas Frequently Used in Podiatry

3.8. Application in Otorhinology of Pharmaceutical Forms for Topical Administration

3.8.1. Introduction
3.8.2. Common Pathologies
3.8.3. Master Formulas Frequently Used in Otorhinology

Module 4. Liquid Dosage Forms for Oral Administration

4.1. Oral Solutions

4.1.1. Solubility and Factors Involved in this Process
4.1.2. Solvents
4.1.3. Production
4.1.4. Quality Control
4.1.5. Potential Problems in Production

4.2. Suspensions and Syrups

4.2.1. Important Aspects
4.2.2. Production
4.2.3. Quality Control

4.3. Sachets

4.3.1. Production

4.4. Application in Pediatrics of Liquid Oral Pharmaceutical Forms

4.4.1. Common Pathologies
4.4.2. Common Master Formulas

4.5. Application of in Geriatrics of Liquid Oral Pharmaceutical Forms 

4.5.1. Common Pathologies
4.5.2. Common Master Formulas

Module 5. Solid Dosage Forms for Oral Administration

5.1. Capsules

5.1.1. Definition and General Aspects
5.1.2. Types

5.1.2.1. Hard Gelatin Capsules
5.1.2.2. Soft Gelatin Capsules
5.1.2.3. Gastroresistant Capsules

5.1.3. Production of Capsules
5.1.4. Excipients Capsules

5.2. Tablets I

5.2.1. Definition
5.2.2. Types
5.2.3. Advantages and Disadvantages.
5.2.4. Preformulation and Property Analysis
5.2.5. Flow Properties
5.2.6. Formulation

5.2.6.1. Types of Excipients

5.2.6.1.1. Diluents
5.2.6.1.2. Binders
5.2.6.1.3. Disintegrants
5.2.6.1.4. Lubricants

5.2.6.2. Direct Compression Excipients

5.2.6.2.1. Cellulose Derivatives
5.2.6.2.2. Starch Derivatives
5.2.6.2.3. Sugars
5.2.6.2.4. Mineral Products

5.2.7. Compression Methods

5.2.7.1. Wet Granulation

5.2.7.1.1. Advantages and Disadvantages
5.2.7.1.2. Granulation and Compression Process

5.2.7.2. Dry Granulation

5.2.7.2.1. Advantages and Disadvantages
5.2.7.2.2. Features

5.2.7.3. Direct Compression

5.2.7.3.1. Advantages and Disadvantages
5.2.7.3.2. Compression Process

5.2.8. Quality Control
5.2.9. Compression Machines

5.2.9.1 Types

5.2.9.1.1. Eccentric Compression Machines
5.2.9.1.2. Rotary Compression Machines

5.3. Tablets II

Module 6. Pharmaceutical Forms of Administration in Mucous Membranes

6.1. Oral Mucosa

6.1.1. Features
6.1.2. Pathologies

6.2. Application in Dentistry

6.2.1. Introduction
6.2.2. Common Pathologies
6.2.3. Common Master Formulas

6.3. Vaginal Mucosa

6.3.1. Features
6.3.2. Ovules

6.3.2.1. Production
6.3.2.2. Excipients
6.3.2.3. Quality Control

6.3.3. Pathologies
6.3.4. Usual Master Formulas in Gynecology

6.4. Rectal Mucosa

6.4.1. Enemas

6.4.1.1. Production
6.4.1.2. Excipients
6.4.1.3. Quality Control

6.4.2. Suppositories

6.4.2.1. Production
6.4.2.2. Excipients
6.4.2.2. Quality Control

6.4.3. Enemas

6.4.3.1. Production
6.4.3.2. Excipients
6.4.3.3. Quality Control

6.4.4. Suppositories and Ovules

6.4.4.1. Production
6.4.4.2. Excipients
6.4.4.3. Quality Control

Module 7. Sterile Dosage Forms

7.1. Definition of Sterile in Master Formulation
7.2. Expiration Dates of Sterile Dosage Forms

7.2.1. Protocols for Producing Sterile Products

7.2.1.1. Work GP
7.2.1.2. Microbiological Control SOPs
7.2.1.3. Lyophilization Protocol

7.3. Sterilization

7.3.1. Heat Sterilization

7.3.1.1. Humid Heat
7.3.1.2. Dry Heat

7.3.1.2.1. Sterilization of Oils
7.3.1.2.2. Sterilization of Glass Materials
7.3.1.2.3. Tindalization

7.3.2. Sterilization by Filtration

7.3.2.1. Types of Filtration

7.3.3. Other Types of Sterilization
7.3.4. Disinfectants

7.3.4.1. Most Frequent Disinfectants

7.4. External Sterile Pharmaceutical Forms. Eye Drops and Ointments
7.5. Internal Sterile Pharmaceutical Forms: Parenteral and Lyophilized

Module 8. Essential Oils in Master Formulation

8.1. Definition of Essential Oil Extraction Processes

8.1.1. Extraction Process

8.2. Quality Criteria Concept of Chemotype Identification Method (Chromatography and Mass Spectrophotometer)

8.2.1. Concept of Chemotype
8.2.2. Method of Identification

8.2.2.1 Chromatography
8.2.2.2. Mass Spectrophotometry

8.3. Instructions for Use of Essential Oils. Pharmaceutical Forms and Routes of Administration. Precautions and Contraindications. Special Recommendations in Pregnancy and Lactation

8.3.1. Topical Route
8.3.2. Oral
8.3.3. By Inhalation

8.4. Essential Oils Most Commonly Used Topically

8.4.1. Pregnancy and Breastfeeding
8.4.2. Pediatrics

8.5. Essential Oils Most Commonly Used Orally

8.5.1. Exotic Basil (Ocinum Basilicum)
8.5.2. Provence Cypress (Cupressus Sempervivens Var. Strict)
8.5.3. Ginger (Zingiber Officinale)
8.5.4. Lavander (Lavándula Angustifolia)
8.5.5. Lemon (Citrus Limón)
8.5.6. Roman Manzanilla (Chamaemelum nobile)
8.5.7. Compact Oregano (Origanum Compactum)

8.6. Essential Oils Most Commonly Used Via Inhalation and Diffuser
8.7. Formulas Most Commonly Used in Dermatology. Dilution Percentages, Vegetable Oils as Excipients or Coadjuvants. Podiatry
8.8. Master Formulas with Essential Oils Frequently Used in Veterinary Medicine
8.9. Master Formulas with Essential Oils Frequently Used in Gynecology

Module 9. Excipients and Bases Used in Master Formulation

9.1. Water, the Most Commonly Used Excipient

9.1.1. Types of Water Used in Master Formulation

9.1.1.1. Purified Water
9.1.1.2. Water for Injectables

9.1.2. Procurement

9.2. Simple Excipients

9.2.1. Non-Aqueous Excipients
9.2.2. Other Commonly Used Excipients
9.2.3. Excipients of Obligatory Declaration

9.3. Compound Excipients

9.3.1. Solid Oral Forms
9.3.2. Liquids Oral Forms
9.3.3. Compound Bases

Module 10. Adjuvants in Individualized Formulation

10.1. Preservatives

10.1.1. Antioxidants
10.1.1. Antimicrobials

10.2. Expiration of Master Formulas
10.3. Correctors of Organoleptic Characteristics of a Formula

10.3.1. Flavorings
10.3.2. Aromatizers
10.3.3. Dyes

Module 11. Basic Physical-Chemical Operations for Processing and Control of Products

11.1. Volume Measurement Units, Volumetric Material, Calibration, Cleaning and Recommendations for Use
11.2. Determination of Mass: Mass Units, Scales and Weighing Methods Verification and Calibration
11.3. Concentration: Concept and Expression. Units
11.4. Dilution Techniques. Realization and Calculations
11.5. Density: Concept, Determination and Applications
11.6. Temperature Measurement
11.7. Viscosity: Concept, Determination and Applications
11.8. Melting Point: Concept and Determination
11.9. Solidification Point: Concept and Determination
11.10. Determination of pH. Fundamental Concepts

A unique, key and decisive training experience to boost your professional development”