A comprehensive compendium of the most advanced knowledge and techniques in nutritional genomics that offers physicians the opportunity to update themselves as experts in this innovative area of intervention”

The Master's Degree in Nutritional Genomics and Precision Nutrition is unique because it includes a wide range of innovative topics and state-of-the-art results in the field of nutrigenetics and nutrigenomics. 

The educational program covers everything a health professional needs to know about this new specialty. The material is organized in such a way as to advance knowledge without leaving any doubts or gaps in information. It is the best program on the market, because it offers the opportunity to learn about all of the innovations in the field of nutritional genomics online, including specific modules on laboratory techniques and statistics. 

The content includes everything new in the broad field of nutritional genomics, such as nutrigenetics, nutrigenomics, epigenetics, metabolomics, market status and laboratory techniques, among other things. There is a selection of scientific articles, high-level studies, innovative results and books that students will be able to access and study. 

In addition, this program is innovative in that it includes practical sections on the current state of the market that offer a realistic, practical and up-to-date view for health professionals who require a 360º vision of the subject. The practical units help to students obtain the critical capacity and deep knowledge of the subject matter that is required for them to know how to apply it in clinical practice. 

This program provides students with specific tools and skills to successfully develop their professional activity in the field of Nutritional Genomics and Precision Nutrition. As it is a Master's Degree, students are not bound by fixed schedules or the need to move to another physical location, rather, they can access the content at any time of the day, balancing their professional or personal life with their academic life. 

This Master’s Degree is the best investment you can make in selecting a refresher program to update your knowledge in Nutritional Genomics and Precision Nutrition" 

This Master’s Degree in Nutritional Genomics and Precision Nutrition contains the most complete and up-to-date scientific program on the market. The most important features of the program include: 

• The development of case studies presented by experts in Nutritional Genomics and Precision Nutrition
• The graphic, schematic and practical contents of the course are designed to provide all the essential information required for professional practice
• Practical exercises where the self-assessment process can be carried out to improve learning
• Special emphasis on innovative methodologies in Nutritional Genomics and Precision Nutrition
• Theoretical lessons, questions to the expert, debate forums on controversial topics, and individual reflection assignments
• Content that is accessible from any fixed or portable device with an Internet connection

This Master’s Degree is the best investment you can make in selecting a refresher program to update your knowledge in Nutritional Genomics and Precision Nutrition"

Its teaching staff includes professionals belonging to the field of nutrition, who contribute their work experience to this program, as well as renowned specialists from leading societies and prestigious universities. 

The multimedia content, developed with the latest educational technology, will provide the professional with situated and contextual learning, i.e., a simulated environment that will provide immersive training programmed to train in real situations. 

This program is designed around Problem-Based Learning, whereby the professional must try to solve the different professional practice situations that arise throughout the program. To do so, the professional will be assisted by an innovative interactive video system created by renowned and experienced experts in Nutritional Genomics and Precision Nutrition. 

This program offers training in simulated environments, which provides an immersive learning experience designed to train for real-life situations"

This 100% online program will allow you to balance your studies with your professional work while increasing your knowledge in this field"

The structure of the contents has been designed by a team of professionals who possess extensive knowledge of the implications of training in daily practice, who are aware of the current relevance of Nutritional Genomics and Precision Nutrition training; and are committed to quality teaching using new educational technologies. 

We have the most complete and up-to-date Scientific Program on the Market” 

Module 1. Introduction to Nutritional Genomics and Precision Nutrition 

1.1. Human Genome 

1.1.1. DNA Discovery 
1.1.2. Year 2001 
1.1.3. Human Genome Project 

1.2. Variations of Interest in Nutrition 

1.2.1. Genomic Variations and the Search for Disease Genes
1.2.2. Environment vs. Genetic Factor and Heritability
1.2.3. Differences between SNPs, Mutations and CNVs

1.3. The Genome of Rare and Complex Diseases 

1.3.1. Examples of Rare Diseases
1.3.2. Examples of Complex Diseases
1.3.3. Genotype and Phenotype

1.4. Precision Medicine

1.4.1. Influence of Genetics and Environmental Factors in Complex Diseases
1.4.2. Need for Precision The Problem of Missing Heritability Concept of Interaction

1.5. Precision Nutrition vs. Community Nutrition

1.5.1. The Principles of Nutritional Epidemiology
1.5.2. Current Bases of Nutritional Research
1.5.3. Experimental Designs in Precision Nutrition

1.6. Levels of Scientific Evidence

1.6.1. Epidemiological Pyramid
1.6.2. Regulation
1.6.3. Official Guides

1.7. Consortia and Major Studies in Human Nutrition and Genomic Nutrition 

1.7.1. Precision4Health Project 
1.7.2. Framingham 
1.7.3. PREDIMED. 
1.7.4. CORDIOPREV 

1.8. Current European Studies 

1.8.1. PREDIMED Plus 
1.8.2. NU-AGE 
1.8.3. FOOD4me
1.8.4. EPIC 

Module 2. Laboratory Techniques for Nutritional Genomics 

2.1. Molecular Biology Laboratory 

2.1.1. Basic Instructions
2.1.2. Basic Material
2.1.3. Accreditations Required in the U.S.

2.2. DNA Extraction

2.2.1. From Saliva
2.2.2. From Blood
2.2.3. From Other Fabrics

2.3. Real-Time PCR

2.3.1. Introduction - History of the Method
2.3.2. Basic Protocols Used
2.3.3. Most Used Equipment

2.4. Sequencing

2.4.1. Introduction - History of the Method
2.4.2. Basic Protocols Used
2.4.3. Most Used Equipment

2.5. High-throughput

2.5.1. Introduction - History of the Method
2.5.2. Examples of Human Studies

2.6. Gene Expression - Genomics - Transcriptomics

2.6.1. Introduction - History of the Method
2.6.2. Microarrays
2.6.3. Microfluidic Cards
2.6.4. Examples of Human Studies

2.7. Omics Technologies and their Biomarkers 

2.7.1. Epigenomics 
2.7.2. Proteomics 
2.7.3. Metabolomics 
2.7.4. Metagenomics 

2.8. Bioinformatics Analysis 

2.8.1. Pre- and Post-Computing Bioinformatics Programs and Tools
2.8.2. GO Terms, Clustering of DNA Microarray Data
2.8.3. Functional Enrichment, GEPAS, Babelomics

Module 3. Biostatistics for Nutritional Genomics 

3.1. Biostatistics

3.1.1. Human Studies Methodology
3.1.2. Introduction to Experimental Design
3.1.3. Clinical Studies

3.2. Statistical Aspects of a Protocol

3.2.1. Introduction, Objectives, Description of Variables
3.2.2. Quantitative Variables
3.2.3. Qualitative Variables 

3.3. Design of Clinical Studies in Humans, Methodological Guidelines

3.3.1. Designs with 2 treatments 2x2 
3.3.2. Designs with 3 treatments 3x3 
3.3.3. Parallel, Cross-Over, Adaptive Design
3.3.4. Sample Size Determination and Power Analysis 

3.4. Evaluation of Treatment Effect 

3.4.1. For Parallel Design, for Repeated Measurements, for Cross-Over Design
3.4.2. Randomization of the Order of Treatment Assignment
3.4.3. Carry-Over Effect (Wash Out)

3.5. Descriptive Statistics, Hypothesis Testing, Risk Calculation

3.5.1. Consort, Populations
3.5.2. Study Populations
3.5.3. Control Group
3.5.4. Subgroup Analysis Types of Studies 

3.6. Statistical Errors 

3.6.1. Measurement Errors 
3.6.2. Random Error 
3.6.3. Systematic Error 

3.7. Statistical Bias 

3.7.1. Selection Bias 
3.7.2. Observation Bias 
3.7.3. Assignment Bias 

3.8. Statistical Modeling 

3.8.1. Continuous Variable Models 
3.8.2. Categorical Variables Models 
3.8.3. Linear Mixed Models 
3.8.4. Missing Data, Flow of Participants, Presentation of Results
3.8.5. Adjustment for Baseline Values, Transformation of Response Variable: Differences, Ratios, Logarithms, Over Evaluation

3.9. Statistical Modeling with Co-Variables 

3.9.1. ANCOVA 
3.9.2. Logistic Regression for Binary and Count Variables 
3.9.3. Multi-Variant Analysis 

3.10. Statistical Programs 

3.10.1. The R 
3.10.2. SPSS 

Module 4. Nutrigenetics I

4.1. Nutrigenetics Authorities and Organizations 

4.1.1. NuGo
4.1.2. ISSN 
4.1.3. Evaluation Committees 

4.2. GWAS I Studies 

4.2.1. Population Genetics - Design and Use 
4.2.2. Hardy-Weinberg Law 
4.2.3. Linkage Imbalance 

4.3. GWAS II 

4.3.1. Allelic and Genotypic Frequencies 
4.3.2. Gene-Disease Association Studies
4.3.3. Association Models ( Dominant, Recessive, Co-dominant) 
4.3.4. Genetic Scores 

4.4. The Discovery of Nutrition-Related SNPs 

4.4.1. Key Studies-Design 
4.4.2. Main Results 

4.5. The Discovery of SNPs Associated with Nutrition-Related Diseases (Diet-Depended) 

4.5.1. Cardiovascular Diseases
4.5.2. Diabetes Mellitus Type II 
4.5.3. Metabolic Syndrome 

4.6. Main Obesity-Related GWAS 

4.6.1. Strengths and Weaknesses 
4.6.2. The FTO Example 

4.7. Circadian Control of Intake

4.7.1. Gut-Brain Axis
4.7.2. Molecular and Neurological Basis of the Brain-Gut Connection 

4.8. Chronobiology and Nutrition 

4.8.1. Central Clock 
4.8.2. Peripheral Clocks 
4.8.3. Circadian Rhythm Hormones 
4.8.4. Intake Control (Leptin and Ghrelin) 

4.9. SNPs related to Circadian Rhythms 

4.9.1. Regulatory Mechanisms of Satiety 
4.9.2. Hormones and Intake Control 
4.9.3. Possible Pathways Involved 

Module 5. Nutrigenetics II - Key Polymorphisms 

5.1. Obesity-Related SNPs 

5.1.1. The Tale of the Obese Monkey
5.1.2. Appetite Hormones 
5.1.3. Thermogenesis 

5.2. Vitamin-Related SNPs 

5.2.1. Vitamin D 
5.2.2. B Complex Vitamins 
5.2.3. Vitamin E 

5.3. Exercise-Related SNPs 

5.3.1. Strength vs. Competition
5.3.2. Sports Performance 
5.3.3. Injury Prevention/Recovery 

5.4. Oxidative Stress/Detoxification-related SNPs 

5.4.1. Genes Encoding Enzymes 
5.4.2. Anti-Inflammatory Processes 
5.4.3. Phase I+II of Detoxification 

5.5. SNP related to Addictions 

5.5.1. Caffeine 
5.5.2. Alcohol 
5.5.3. Salt 

5.6. SNP related to Flavor 

5.6.1. Sweet Taste 
5.6.2. Salty Taste 
5.6.3. Bitter Taste 
5.6.4. Acid Taste 

5.7. SNP vs. Allergies vs Intolerances 

5.7.1. Lactose 
5.7.2. Gluten 
5.7.3. Fructose 

5.8.  PESA Study 

Module 6. Nutrigenetics III

6.1. SNPs Predisposing to Complex Nutrition-Related Diseases -- Genetic Risk Scores (GRS) 
6.2. Type II Diabetes 
6.3. Hypertension 
6.4. Atherosclerosis 
6.5. Hyperlipidemia 
6.6. Cancer 
6.7. The Exposome Concept 
6.8. Metabolic Flexibility Concept 
6.9. Current Studies-Challenges for the Future 

Module 7. Nutrigenomics 

7.1. Differences and Similarities with Nutrigenetics 
7.2. Bioactive Components of Diet on Gene Expression 
7.3. The Effect of Micro and Macro Nutrients on Gene Expression
7.4. The Effect of Dietary Patterns on Gene Expression 

7.4.1. The Mediterranean Diet Example

7.5. Main Studies in Gene Expression 
7.6. Genes Related to Inflammation 
7.7. Genes Related to Insulin Sensitivity
7.8. Genes related to Lipid Metabolism and Adipose Tissue Differentiation
7.9. Genes Related to Atherosclerosis
7.10. Genes Related to the Myosceletal System 

Module 8. Metabolomics-Proteomics 

8.1. Proteomics 

8.1.1. Principles of Proteomics 
8.1.2. The Flow of Proteomics Analysis 

8.2. Metabolomics 

8.2.1. Principles of Metabolomics 
8.2.2. Targeted Metabolomics 
8.2.3. Non-Targeted Metabolomics 

8.3. The Microbiome/Microbiota 

8.3.1. Microbiome Data 
8.3.2. Human Microbiota Composition 
8.3.3. Enterotypes and Diet

8.4. Main Metabolomic Profiles 

8.4.1  Application to Disease Diagnosis 
8.4.2. Microbiota and Metabolic Syndrome 
8.4.3. Microbiota and Cardiovascular Diseases Effect of the Oral and Intestinal Microbiota 

8.5. Microbiota and Neurodegenerative Diseases 

8.5.1. Alzheimer’s Disease 
8.5.2. Parkinson’s Disease 
8.5.3. ALS 

8.6. Microbiota and Neuropsychiatric Diseases

8.6.1. Schizophrenia
8.6.2. Anxiety, Depression, Autism

8.7. Microbiota and Obesity 

8.7.1. Enterotypes 
8.7.2. Current Studies and State of Knowledge

Module 9. Epigenetics 

9.1. History of Epigenetics - The Way I Eat and Inheritance for My Grandchildren
9.2. Epigenetics vs. Epigenomics 
9.3. Methylation 

9.3.1. Examples of Folate and Choline, Genistein 
9.3.2. Examples of Zinc, Selenium, Vitamin A, Protein Restriction

9.4. Histone Modification

9.4.1. Examples of Butyrate, Isothiocyanates, Folate and Choline
9.4.2. Examples of Retinoic Acid, Protein Restriction

9.5. MicroRNA

9.5.1. Biogenesis of MicroRNAs in Humans
9.5.2. Mechanisms of Action-Regulating Processes 

9.6. Nutrimiromics 

9.6.1. Diet-Modulated MicroRNAs 
9.6.2. MicroRNAs involved in Metabolism 

9.7. Role of MicroRNAs in Diseases 

9.7.1. MicroRNA in Tumorogenesis 
9.7.2. MicroRNAs in Obesity, Diabetes and Cardiovascular Diseases

9.8. Gene Variants that Generate or Destroy Binding Sites for MicroRNAs 

9.8.1. Main Studies 
9.8.2. Results in Human Diseases 

9.9. MicroRNA Detection and Purification Methods

9.9.1. Circulating MicroRNAs
9.9.2. Basic Methods Used 

Module 10. Current Market State 

10.1. DTC (Direct-to-Consumer) Tests 

10.1.1. Pros and Cons 
10.1.2. Myths of Early DTCs 

10.2. Quality Criteria for a Nutrigenetic Test 

10.2.1. SNP Selection 
10.2.2. Interpretation of Results 
10.2.3. Laboratory Accreditations 

10.3. Health Professionals 

10.3.1. Training Needs 
10.3.2. Criteria of Professionals Applying Genomic Nutrition 

10.4. Nutrigenomics in the Media 
10.5. Integration of Evidence for Personalized Nutritional Counseling 
10.6. Critical Analysis of the Current Situation 
10.7. Discussion Work 
10.8. Conclusions, Use of Nutritional Genomics and Precision Nutrition as Prevention 

A unique, key, and decisive educational experience to boost your professional development”